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"… ESR1 [gene] amplification is an uncommon mechanism for estrogen receptor overexpression in ovarian cancer occurring in about 2.1% of the total number of ovarian cancers. In general, this frequency parallels the fraction of ovarian cancers reported to show complete response to antiestrogenic [anti-hormonal] therapies. Given the strong predictive power of ESR1 [gene] amplification for response to tamoxifen in breast cancer, an evaluation of such treatments in ESR1 [gene] amplified ovarian cance Note: I wrote most of this post Friday night, but I had to sit with it for a while to see if I really wanted to post it. Things are okay now. S and I have talked about things, but I still feel like I need to vent, and show the ugly side of infertility (not that there is a pretty one). I had my 4th IUI. Woo hoo. This one hurt more than the others. A different nurse did this one and man was she rough with the speculum. Ugh. Pinching and pushing and wrenching it all around. My cervix is n
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